Sentence examples for modest disease from inspiring English sources
However, the dosing schedule used for these experiments induced only unsustained and modest disease control.
GWAS has been widely accepted as a primary approach for gene finding and achieved huge success in identifying genes conferring modest disease risks in human.
An individual predisposing variant may well exhibit only weak or modest disease risk in a sample even while it may show large risk in other samples.
Additional non-MHC susceptibility loci have been identified; however, when examined individually each of these loci only confer modest disease risk and is of limited utility in disease prediction.
In two phase II clinical trials, modest disease control was observed in patients receiving erlotinib as a single agent.
These findings are consistent with the modest disease control we also observed in our case treated with panitunumab and sorafenib.
However, variants previously reported to be causative in LQTS have subsequently been shown to be rare variants with only a modest disease-modifying effect or even non-pathogenic.
The Dutch study suggests a modest disease-free survival advantage for the high-dose arm, but further follow up is required to ascertain statistical significance (P = 0.057, two-sided, at the early analysis).
With genotype prevalences up to one thousand times higher than expected from the phenotype prevalence in the general population, we suspect a high number of these genetic variants to be only modest disease-modifiers or even non-pathogenic.
Second, assessing baseline creatinine values by the MDRD equation as in previous reports may have exposed our study methodology to the risk of inclusion of patients with modest chronic disease not captured by the APACHE II definitions as having end-stage renal disease or RRT dependence.
However, our study has a small sample size resulting in low power to detect minor to modest genotype-disease associations and gene-environment interactions, therefore such associations cannot be ruled out.
