The number of high loan-to-value mortgages on offer to new buyers increased during the year, and the CML said there was "a modest but discernible increase" in lending at these levels.
Alcohol use and coffee consumption were modest, but discernible contributors in men and women.
In addition, combined exposure of cells to celecoxib and ABL resulted in a modest but discernible decline in the phosphorylation of downstream Akt target GSK-3 β.
Additionally, although expression of the v33925 RNAi transgene led to a modest but statistically discernible decrease in PPT1 enzyme activity (Fig. 5B), expression of the v 33926 RNAi transgene did not alter PPT1 enzyme activity (Fig. 5C).
This is a time of retrospectives often rummaging to gather films by directors of some discernible personality but only modest artistic inspiration, and of boxed sets celebrating similarly undistinguished names, but names nonetheless.
Increases in glucose flux revealed no discernible peak and were modest with maximal glucose infusion rates of 9.4, 6.6, 5.5, and 2.8 μmol/kg/min for the 2.0, 1.0, 1.0, and 0.5 units/kg doses, respectively.
Very large doses result in modest increases in glucose flux with no discernible peak action.
Overall, the changes in cardiac gene expression in this high-prorenin model of arterial hypertension and cardiac hypertrophy were modest and apparently insufficient to cause any discernible effects on cardiac histology other than hypertrophy, despite an increase in Col1 mRNA levels.
Thanks to the monster turbocharger and fancy electronics, this pocket workhorse produces 258 foot-pounds of torque at a modest 2,500 engine revolutions per minute, with no discernible "turbo lag".
However, even with a small sample size, the lack of any discernible effect on other markers of inflammation coupled with the very modest clinical changes make it unlikely that ISIS-CRPRx will be an adequately effective drug for treatment of rheumatoid arthritis when compared with other currently available and experimental therapies.
