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The modest diminution of B cells constitutes a difference with that found in adults, for instance Monserrat et al. [31] described severe abnormality of circulating B lymphocytes associated with mortality.
Remarkably, aptamers blocked more than one inhibitor simultaneously, and a modest diminution of aptamer binding (3 10 fold) was only seen at the highest total inhibitor concentration (2400 nM) (Figure 1).
Western blots showed modest diminution of RPS13 at 4 hours and a marked diminution of RPS13 at 24 and 48 hours in the absence of ATc (Figures 3B and S3A).
It is noteworthy, therefore, that there was a small but significant reduction in miR-9-2 expressinn in the Visc-2−/− brain versus controls, suggesting that the deletion of the first exon of Visc-1 has a modest diminution of transcription of the pre-mRNA9-2, which is mostly transcribed from a separate, more proximal, promoter in a neural cell line (Laneve et al. 2010).
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The HER2+ cell line UACC893 displayed modest but significant diminution of tumor cell numbers after 16 days in culture with EZN4150.
Based on limited human or mouse data we predicted a correlation between loss of cavitation and a loss of tumour necrosis factor (TNF -α or inTNF -αor (interferon2– 24]; however, dIFN -γIFN -γ these cytokines in the non-cavitary group was modest and not statistically significant.
We addressed the challenge of mitigation in the event of a modest pandemic scenario, but, in agreement with national strategic policy, we assumed no diminution of standards of care or rationing of clinical services.
"There has been no apparent diminution.
"There's a subtle diminution in prestige".
There is a diminution of complexity.
Robert: Modest.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com