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However, the PSA test has only modest diagnostic specificity and positive predictive value for prostate cancer detection at commonly used cut-points.
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Also, TPA has low diagnostic specificity (29.2%).
Subsequent analysis of a modest number of patients using this 18-protein ELISA panel provided highly promising results, with diagnostic specificity and selectivity approaching 90%, including correct identification of samples from patients that would later develop AD but who were presymptomatic at the time of sampling.
The developed assay showed diagnostic sensitivity of 98% and diagnostic specificity of 100%.
Diagnostic sensitivity and diagnostic specificity of the spoligo biochip assay were 99.1% and 100%, respectively.
Diagnostic specificity and sensitivity of biomarkers are currently weighed against creatinine-based criteria.
Diagnostic sensitivity on the validation set varied from 18 to 100% for the five assays while diagnostic specificity was 100%.
Nine pairs of primers were examined for their PCR diagnostic specificity on the 109 isolates.
Results: QuickVue's® diagnostic specificity exceeds that of unaided clinical diagnosis by 29 31%.
And as such tools for diagnostic specificity improve, our use of in-person medical services should become less frequent and more targeted.
Incorporation of such markers into a biomarker panel may improve diagnostic specificity.
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