Sentence examples for modest defects from inspiring English sources
In our hands, primary T cells deficient for either ezrin or moesin alone showed modest defects in T cell function.
Second, only modest defects were observed in fetal liver chimeras, demonstrating that the requirement for ezrin is independent of hematopoietic-lineage cells.
Given the moderate rescue of the anteroposterior patterning defects of grkΔFRT ovaries by the grkGLSmut transgene, we expected only modest defects in the transport and anterior localization of grkGLSmut transcripts.
The mutants in that complementary study showed modest defects in translation activity.
TRPV4 knockout mice also exhibited modest defects in heat-evoked pain sensation, though this phenotype was virtually absent in TRPV3/TRPV4 double knockout mice.
Overall, toeprint band intensity did not correlate well with translation activity, suggesting that something else regulates the modest defects that were identified in that study.
However, mutating all five sites of PQR to alanine resulted in only a modest defect in NHEJ.
Our finding of slight period lengthening relative to controls even at 18°C is consistent with a modest defect, with core clock effects getting stronger gradually as the temperature increases.
Intriguingly, cells with mutations in PCNA produce only modest cohesion defects while cells with mutations in Ctf18p exhibit high levels of premature separation [10], [11], [26].
In contrast, rad61 ctf7 double mutant cells exhibit robust growth at 30°C, although these cells are growth inhibited at 18° and exhibit at least modest growth defects at both 23°C and 37°C (Figure 2).
