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The 3′ terminal AU content makes modest, but detectable contributions.
We hypothesized that in the tightly regulated somatic cell haploinsufficient changes, even of a critical gene like NF1, will be modest but detectable by microarray.
The time trends in these anthropometric variables is relatively stable, with a modest but detectable increase of weight at birth, conditional on gestational age and other covariates.
Mec1-HAp association with the VI-R telomere in yku70Δ cells showed a modest but detectable increase in Mec1-HAp association as cells entered late S-phase, with a subsequent reduction as the cells entered G2/M (Fig. 6a c).
The time trends in these anthropometric variables during the 5 year period of observation in this study is roughly stable, with a modest but detectable increase of weight at birth observed after adjustment for gestational age and other variables.
However, given the fact that Sox2-het mice have a modest, but detectable, defect in growth, the above results leave open the possibility that p27 and Sox2 simply have opposite effects on growth that balance each other.
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In chlorpromazine-treated cells the internalisation of ACT and β2 was more modest, but still detectable (≈20%) (Fig. 3 A and B, respectively), suggesting that a clathrin-independent, ACT-induced internalisation mechanism might be operating in parallel in the ACT-treated cells.
It is intriguing that we consistently observed a modest, but readily detectable degree of potentiated inhibition of MET phosphorylation by erlotinib, with and without SU11274, both in A549 and in H1975 cells.
Almost every known chemical compound will dissolve in water to a small (but detectable) extent.
As shown in figure 1, i.v. inoculation of HEK293-pmeLUC cells in healthy nude mice caused a modest, barely detectable, increase in luminescence, except for the third mouse from the left, which showed a strong signal at site of injection in the tail, likely due to tissue damage and ATP release during the injection.
This modest, although detectable biochemical change, which reflects the small reduction in cellular ATP content reported in figure 1 D, likely accounts for reduced mTOR signaling [ 8] in Phoenix cells grown in the absence of glucose.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com