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(Ms. Ipcar, now 98, went on to have a modest but active career).
His life in retirement was modest but active, perhaps epitomized by his habit of taking a brisk morning walk, or "constitutional," along the sidewalks of Independence, Mo.
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Given the modest but definite active of temozolomide in the treatment of brain metastases from melanoma and the possibility of synergy between temozolomide and lomustine, a multicentre phase I/II trial was conducted to determine the maximum tolerated dose (MTD), safety and efficacy of the combination of these drugs.
Both enzymes showed modest but reproducible ATPase activity, and mutation of conserved active site residues resulted in the complete loss of activity.
Immunization of mice with BDES-PbPSOP12 confers modest but significant transmission-blocking activity in vivo by active immunization (53.1% reduction in oocyst intensity, 10.9% reduction in oocyst prevalence).
Recombinant production has been studied in filamentous fungi (Conesa et al.2000 Irie et al.2001 Li et al.2001 Mayfield et al.1994 Stewart et al.1996), yeasts (Jiang et al.2008a), bacterial (Whitwam &Tien 1996) and insect (Johnson et al.1992; Pease et al.1991) hosts with successful production but modest yields of active enzyme.
Response rate was modest but included all mainland Scottish regions with active stroke services.
(Orient has a modest though active yacht club).
A 12-month course of active therapy was associated with a modest but statistically significant improvement in forced vital capacity (FVC), but no change in diffusing capacity for carbon monoxide.
Daily active users of Facebook in December totaled 757 million, up a modest but in-line 22%.
Modest, but real.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com