Sentence examples for modest bioavailability from inspiring English sources

Our study suggests that the modest bioavailability of NU7026 is not due to first pass metabolism as the relative proportion of administered dose present as parent or metabolites are similar after i.v., i.p. and p.o. administration.

Normally they have very low bioavailability," he says.

The lead compound demonstrated very good oral bioavailability in mice, slow metabolic degradation, modest distribution into the brain and a remarkable anti-inflammatory efficacy in carrageenan-induced mouse paw edema model.

Initial in vivo testing has revealed good oral bioavailability in a mouse PK study and modest in vivo efficacy in a Plasmodium berghei mouse model of malaria.

Importantly, because O2⋅− can spontaneously react with nitric oxide (NO) to form OONO− at a rate 3 times faster than O2⋅− dismutation by SOD, modest increases of O2⋅− can result in a great reduction of NO bioavailability and increased formation of OONO−, a very strong oxidant with the potential to produce multiple cytotoxic effects [98], [99].

A modest suppression of stimulated cortisol in glucocorticoid-untreated RA patients is not associated with decreased cortisol bioavailability.

Greger, J.L. Nondigestible carbohydrates and mineral bioavailability.

Mineral bioavailability and metabolism is complex.

Gamma tocotrienol in GDT showed superior bioavailability whilst delta tocotrienol showed less bioavailability compared to TRF.

A bioavailability score was also obtained to evaluate the bioavailability of ingredients in FFDS.

"There is definitely potential for improving the bioavailability of these particles".