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The joint analysis of both genes by means of tagging SNPs and haplotypic association analyses showed a modest association for insulin and HOMA, although for glucose values we only observed a trend toward association.
Statistical analysis showed a modest association for Stmn2 but a highly significant association for the Rarb locus [ 31 ].
Most showed no association to measures of efficacy, while one showed modest association for a particular haplotype in only a subset of the STAR*D sample [ 70].
In a genome-wide linkage study, the strongest signals that may be specific to postpartum mood symptoms were on 1q21.3-q32.1 and 9p24.3-p22.3, with modest association for Hemicentin gene SNPs on chromosome 1 [ 16].
These analyses showed an overrepresentation of the Pax5 (V$Pax5.1 z-score = 87.59, overrepresentation: 2.86; V$Pax5.2 z-score = 78.62, overrepresentation: 3.95) and Pax9 consensus motifs (V$Pax9.1 z-score = 73.71; overrepresentation: 3.63) with a modest association for Pax8 (V$Pax8.1 z-score = 5.46, overrepresentation: 1.07).
Regression analyses (Table 2) showed correspondingly strong evidence of a large association between the introduction of the CDF and increased prescribing in England compared with Wales for bevacizumab (PVR=3.28 (95% CI 2.59 4.14), P<0.001), but only marginal evidence of a modest association for sorafenib (PVR=1.29 (95% CI 1.00 1.67), P=0.05).
Similar(54)
For cardiopulmonary mortality, we observed significant associations for PM2.5 mass, nitrate, sulfate, and silicon, with more modest associations for zinc.
This promising new technology has the potential for finding modest associations for polygenic diseases such as endometriosis.
Initially evidence for linkage with schizophrenia was reported near RGS4 at 1q21-22 [ 1, 2] and several association studies also suggested modest associations for certain RGS4 gene variants [ 3- 9].
b) A strong association of kynurenine to its toxic metabolite 3HK exclusively in controls contrasted with modest associations for neuroprotective indices in all groups c) Medication moderated the production of 3KA in the ADHDmed group.
A review of 14 published association studies (2812 cases and 10 843 controls) of the Val66Met variant in the BDNF gene in adults with unipolar major depression showed very modest associations for males only.
Related(20)
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