Sentence examples for modest alterations of from inspiring English sources

Operations on the basis of the solution space permit modest alterations of the transients toward the target steady state.

In contrast, even at high doses, fructose produces only modest alterations of glucose homeostasis.

We find that a modest alteration of an initially 'scale-free' network can usefully improve robustness against attack, particularly when the fraction of attacked nodes is small, and we identify modification schemes that are most effective for this purpose.

By this view, the protein world ought to consist of one structural archetype put to many different uses, each involving modest alteration of peripheral structure but no major reorganization of the fold.

Thus, a modest alteration of RYGB criteria to include this population would have far-reaching implications for diabetes care.

Modest alteration of glucose tolerance, even within nondiagnostic boundaries, is associated with marked reduction of β-cell mass and function (37).

Even with very high fructose supplementation, there is only a modest alteration of hepatic glucose metabolism, which may merely represent a metabolic adaptation to the consumption of a glycogenic substrate rather than a step toward diabetes.

Nevertheless, a more modest alteration of the CLR RAMP1 interface could be envisaged that results in an allosteric modification of the peptide-binding site (Fig. 3A), with compounds such as BIBN4096BS and MK-0974 asting as a lever between the N-termini of RAMP1 and CLR, breaking nearby interactions which are critical for binding of the peptidic ligand.

We expected that the reduced or absent levels of miR-279, miR-317, and miR-184 in the mutant females would, to some extent, mimic the down-regulation that we had previously observed following receipt of SP. Our observation of modest alterations to SP responses in the miRNA mutant females suggests that the miRNAs may function to buffer noise or stabilize responses to mating.

After a panic at the turn of the millennium about the impact on their industry of online shopping, bricks-and-mortar stores settled into making only modest alterations to their business model or, ostrich-like, trying to ignore it.

Indeed, a modest number of genes exhibit modest alterations in levels of expression with several of these genes near the sites of the indel mutations (Table 4).