Although LBP is recurrent, a large number of treatments addressing this problem have modest clinical benefits and low adherence [ 8, 9].
The increase in sample size created a slight improvement in power, on average, and adequately accounted for an anticipated 10% loss-to-follow up and more modest exercise adherence that we postulated might occur with the higher demands associated with the exercise intervention in the HIGH volume arm of the trial.
The relatively more modest relationships between adherence and HbA1c were expected, because glycemic control is affected by a variety of factors beyond medication adherence, including diet and exercise, degree of insulin deficiency, and adequacy of the prescribed treatment regimen.
If worn, certain models of hip protectors are highly effective at preventing hip fractures from falls in residents of long-term care, but modest acceptance and adherence have limited the effectiveness of hip protectors.
There was not a decrease, but rather there was a modest increase in adherence, with 1.01±0.22% of untreated bacteria and 1.75±0.33% of DFMO-treated bacteria found to be adherent, respectively (Figure 7C).
Even modest increments in adherence could have substantial impacts upon clinical outcomes and costs [ 19- 21].
We found modest variation in adherence rates across the six medical conditions included in this study.
Our study results suggest an at most modest concordance between adherence measures tested in a sample of breast cancer patients receiving endocrine treatment.
Although modest relationships between adherence self-reports and HbA1c are often interpreted as reflecting the limited validity of these measures, this may not be an appropriate conclusion.
However, the actual impact of pay-for-performance on quality is largely unknown [ 41], although recent work suggests that financial incentives has a relatively modest effect on adherence to process measures [ 42].
