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We wished to determine whether the relatively modest activity of trifluralin was the consequence of poor uptake into parasite cells.
Such studies indicate that the modest activity of Co FTS catalysts might very well be attributable to the difficulty to remove chemisorbed oxygen from the metallic surface, rather than to dissociation of CO, which was found to proceed readily at step edge sites.
Again, using different injected mRNA concentrations, the modest activity of the mutant Syndapin suggests little evidence of a dose-dependent effect for the KK→AA mutant.
To our knowledge one study, however, indicates the presence of PDE3 and PDE4 activities as well as modest activity of PDE1 in human islets, and inhibition of PDE3, but not PDE1 and PDE4, was shown to increase insulin secretion [9].
Previously, one single study has shown the presence of PDE3 and PDE4 activities as well as modest activity of PDE1 in human islets [9] and, importantly, that PDE3 inhibition resulted in increased insulin secretion.
Present study highlights the modest activity of St. John's Wort against acute restraint stress induced modification.
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But even so, the effects of this modest activity on the brain were remarkable, Dr. Middleton said.
This could be a possible underlying mechanism to the low-to-modest activity of farnesyltransferase (FTase) inhibitors in clinical phase II and III studies (Sebti and Adjei, 2004).
The composite photocatalyst shows also modest activity for the photodegrading of 4-chlorophenol (4-CP).
Most compounds showed modest activity to inhibit production of nitric oxide (NO) in RAW 264.7 cells induced by lipopolysaccharides (LPS).
We know the mutations associated with developmental syndromes cause a modest activation of MEK activity compared with activating mutations in the activation segment.
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