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The results identified 1 as a propitious hit with modest activities attributed to the concurrent down-regulation of mitogen activated protein kinase kinase/extracellular signal-regulated kinase (MEK) distinctive downstream effectors.
(Co,Ni -doped OMCo,Ni -dopedst activities in acidic media, while the catalytic activity in alkaline media is rather high.
All the complexes were screened in vitro against Mycobacterium tuberculosis and exhibited only modest activities in the micromolar range.
Conclusions: Our results suggest that physical frailty is modifiable with a program of modest activities that can be performed by virtually all older adults.
Although only modest activities were observed, these results suggested that a new series of bioactive cryptophycin analogues might be available by structural modification of the central ring system of the cryptophycins.
However, the roots of Dichrostachys cinerea revealed modest activities with RSA of 27.4% [51].
Similar(49)
From the compounds tested several CB2R activators were identified as having modest activity.
Mammalian target of rapamycin inhibitors possess modest activity against STS; however, resistance develops via MAPK pathway feedback activation.
Cefotaxime is active against penicillin-resistant strains of Streptococcus pneumoniae and has modest activity against the anaerobic bacteria Bacteroides fragilis.
The composite photocatalyst shows also modest activity for the photodegrading of 4-chlorophenol (4-CP).
Oxaliplatin and pemetrexed have each shown modest activity in the treatment of CRPC.
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