Sentence examples for modes of target from inspiring English sources
Molecular docking analysis was performed as well to predict possible binding modes of target compounds with MDM2.
For GPCRs, allosteric mechanisms impart multiple modes of target modulation (positive allosteric modulation (PAM), negative allosteric modulation (NAM), neutral cooperativity, partial antagonism (PA), allosteric agonism and allosteric antagonism).
Alternately, some of these miRNAs may have different modes of target recognition [ 16].
Our simulations also suggest that enhancer clustering itself is sufficient to generate these two modes of target search.
It has been demonstrated that some miRNAs have alternative modes of target recognition that do not require a seed match [ Brennecke et al., 2005; Chi, et al., 2012; Shin et al., 2010].
Such differences in DNA methylation sensitivity are likely due to their different modes of target recognition: the 5-methyl group on C does not affect proper base pairing with gRNA, but might abolish the protein:DNA interaction in the major groove for ZFNs and TALENs.
Two modes of targeting HER2 have been extensively studied in the treatment of HER2-overexpressing breast cancer, both in vitro and clinically.
As discussed above, epigenetic work throws previous modes of targeting individual nutrient consumption into doubt, increasing wariness about substitutability of synthetic or purified substances for whole foods, attention to potentially damaging effects of prior technical 'improvements' to food, and worry about the balance between nutrients in a complex metabolic environment.
Molecular docking studies have inferred the possible binding mode of target compounds against integrase.
Molecular docking analysis was also performed to predict the possible binding mode of target compounds inside the hA3AR and hA2AAR.
The tumbling of truncated oval-nosed projectiles is very prominent, which results in the great uncertainty of deformation and failure mode of target plates.
