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Rhabdomyolysis-associated acute kidney injury can be treated with various modes of renal replacement therapy (RRT) [ 1, 2].
Several studies also established dosing recommendations in patients undergoing various modes of renal replacement therapy [ 1– 5].
The DOse REsponse Multicentre International collaborative initiative (DO-RE-MI) will address the issue of how the different modes of renal replacement therapy are currently chosen and performed.
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Associations between mode of renal replacement therapy and employment rate have not been well characterized.
The mode of renal replacement therapy (intermittent versus continuous) has no impact on patient survival.
Maintenance dialysis therapy is the commonest mode of renal replacement therapy and demand for this service is increasing progressively worldwide.
The tip of the CKD 'iceberg' is manifest in end stage renal disease (ESRD), when, to sustain life, some mode of renal replacement therapy (RRT) becomes necessary.
HD is the most effective mode of renal replacement therapy after renal transplantation, but is expensive and burdensome to the patient.
Peritoneal dialysis has been proven to be a safe and effective mode of renal replacement therapy for patients with end-stage renal disease.
Thus, if the mode of renal replacement therapy was changed during follow-up, a person would contribute to risk time in both subgroups.
Recommendations for patients who have chronic renal failure and who are undergoing intermittent hemodialysis are not appropriate for the critically ill, because of differences in the mode of renal replacement therapy and in pharmacokinetics [ 5].
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