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lncRNA have several modes of function, including neutralizing miRNA and inhibiting transcription of target genomic regions.
However, their modes of function as anti-cancer agents are still largely unknown.
Linking specific pathways or modes of function with genes by the general descriptors provided by Gene Ontology (GO) for zebrafish is problematic due to the incomplete annotation of the zebrafish genome and a deficiency in functional studies.
It is not clear whether these different modes of function are related and potentially coordinated across repeats of the same element, or whether they arise independently from each other.
This lack of overlap could be the consequence of several reasons: (i) different modes of function and kinetics of antagonistic LTβR-Ig LTβR-Igistic anti-LTβR mAb application, (ii) incubation time (3 d treatment with LTβR-Ig vs 10 h treagonisticth agonistic anti-LTβR mapplicationii incubationllectime of different cell types influenced by the treatment vs in vitro cell culture system using MEFs.
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There is, in addition to the three ways of knowing, consideration of the modes of functioning of the sense organs.
Cognitive style, manifested perceptually as field-dependence--field-independence, is a salient dimension influencing characteristic modes of functioning in a diversity of areas.
Photo-sensitive catalysts of the media reactions enable easy input of initial data, output of computational results and control of the dynamics (modes of functioning) of the media.
Sometimes being understood to be disabled triggers acceptance of or accommodation to atypical modes of functioning.
Thus, even healthy people with disabilities often are stigmatized because their embodied modes of functioning strike others as disruptive, however adeptly adaptive and independent these may be.
My research focuses upon delineating processes of developmental change, creating explanatory models of how biological, behavioral, and social-cultural factors act together in development, and detailing how developing organism's own modes of functioning shape their subsequent paths of development.
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