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Galton alluded to this in his original 1880 paper, concluding that "the missing faculty seems to be replaced so serviceably by other modes of conception... Men who declare themselves entirely deficient in the power of seeing mental pictures can nevertheless give life-like descriptions of what they have seen".
Furthermore it is one of the few that compares three modes of conception [ 6, 8] and constitutes one of the largest series on singletons pregnancies after oocyte donation published thus far, with a well defined and age matched control group [ 7, 8] where the medical indication of the oocyte donation treatment for every woman was taken into account.
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The aim of this study is to assess the obstetric and perinatal outcomes of twin pregnancies according to mode of conception.
To collect data on every baby born in one week in the United Kingdom with respect to mode of conception, multiplicity of pregnancy, and outcome.
To study the effects of mode of conception (spontaneous vs. assisted) on health-related quality of life (HRQoL) throughout pregnancy and in the postpartum period.
To evaluate whether older first-time mothers (≥37 years) have higher rates of postpartum depression compared with younger first-time mothers, controlling for mode of conception and known risk factors for postpartum depression.
The working group considered input from the pregnancy experts and the broader research community and included measures addressing the mode of conception, gestational age, fetal growth assessment, prenatal care, the mode of delivery, gestational diabetes, behavioral and mental health, and environmental exposure biomarkers.
The obstetric characteristics differed according to mothers' mode of conception.
Infants' characteristics and outcomes by plurality and mode of conception are shown in Table 2.
Details regarding mode of conception were collected retrospectively from maternal health records.
Neither age nor mode of conception was associated directly with pregnancy related hospital admission.
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