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We next considered how these different binding modes may account for the various activity profiles of compounds toward ERα.
Such alternative modes may account for the heterogeneity of DnaK oligomers observed by single particle electron microscopy (Thompson et al., 2012).
The fact that both proteins appear to bind syntaxin-1 via different binding modes may account for this non-redundancy (Parsaud et al., 2013).
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Comparison of the three-dimensional structures in complex with MHC suggests major differences in hydrogen bonding patterns with H2Kb, despite sharing similar binding modes, which may account for the differences in affinity and immunogenicity.
The lack of amino acid sequence conservation between karyopherin-α and CTNNBL1 therefore reflects a distinct NLS binding mode and may account for the selectivity of the NLS interactions of CTNNBL1.
In vivo microarray data implicated three modes of regulation which may account for over-production of steroids during a depuration phase (when the stressor is removed): P450 enzyme up-regulation, inhibin down-regulation, and luteinizing hormone receptor up-regulation.
As mitochondria in vivo probably spend much of their time synthesizing ATP, this mode of O2− production may account for most of the overall exposure of mitochondria to O2−.
RF and boosting do not require specification of the mode of inheritance and hence may account for non-additive effects.
Our finding that a variant Mig1 site, GTGGGG(A/G/T)(A/T G, is significantly enriched in redundantly repressed promoters, but absent from promoters repressed only by Mig1, suggests that differences in sequence specificity between Mig1 and Mig2 may account for different modes of regulation.
According to default-mode interference hypothesis inefficacious transition from rest to task may account for impaired cognitive task performance [ 13].
Regulatory mechanisms mentioned above may work in combination to produce a variety of expression profiles, where even in bimodal genes one mechanism may account for expression level changes within a single mode of expression and an alternative regulatory mechanism may account for expression level changes between modes of expression.
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CEO of Professional Science Editing for Scientists @ prosciediting.com