We imputed missing BMI values using linear regression on age and sex for complete cases, and the missing values for other categorical variables were imputed by taking the mode values after adjusting for age and sex.
Logistic regression analysis was used to calculate odds ratio (OR) as a measure of association of genotype with IS, under assumptions of additive mode of inheritance, adjusting for established risk factors for IS.
Carriers of the minor allele for rs6717924 were at higher risk of being obese (odds ratio (OR) and [95% CI] = 1.40 [1.06; 1.85], P = 0.018) whereas subjects with the minor allele for rs13426118 were protected against obesity (0.71 [0.55; 0.93], P = 0.013 in an additive mode of inheritance after adjusting for age and sex) (Table 3, Table S3).
Taking immune suppressive medication was no longer a risk factor after adjusting for mode of data documentation.
When adjusting for mode of delivery the effect of age was no longer statistically significant (not shown).
This study aimed to determine whether presentation of the second twin following vaginal delivery of a vertex first twin was associated with poorer maternal or neonatal outcomes, after adjusting for mode of delivery.
We examined the following categories of CD: parental CD, maternal CD only, and paternal CD only, adjusting for mode of delivery, birth order, multiple gestation, mother's age at delivery, and paternal and maternal asthma.
Table 4 shows that adjusting for mode of delivery reduced the risk of infant resuscitation (OR 0.86, 95% CI 0.63 to 1.18) to the point where it was no longer statistically significant, but the additional adjustment did not significantly alter the other estimates.
Neonatal factors associated with mode of delivery after adjusting for all maternal factors are presented in Table 5. Infants delivered by vaginal method or emergency caesarean section were more likely to be associated with the risk of sensorineural hearing loss but less likely to be associated with hyperbilirubinaemia compared with infants delivered by elective caesarean section.
However, adjusting for mode of delivery did not change our results and it is therefore more likely that the higher risk of low Apgar score in publicly insured women in public hospitals is either due to residual confounding in our data or practise differences between public and private hospitals in Western Australia.
