Sentence examples for modern sequencing approaches from inspiring English sources

While these sequencing methods work well on short synthetic DNA strands and could potentially be applied for the development of probes to study genomic samples, Maxam and Gilbert type sequencing is rather time-consuming and cumbersome compared to modern sequencing approaches and so this approach may not be suitable for the routine genome-wide study of epigenetic modifications.

Additionally, chemical mutagenesis particularly in combination with modern sequencing approaches continues to provide an invaluable resource in attempts to complete the functional annotation of the genome (Arnold et al., 2011; Brown et al., 2013; Gondo et al., 2010; Kile et al., 2003; Oliver and Davies, 2012; Probst and Justice, 2010).

Modern high-throughput sequencing approaches (RNA-Seq) enable the most detailed view on transcriptomes offering an unmatched comprehensiveness and single-base resolution.

However, a molecular-taxonomic approach with modern sequencing techniques for the evaluation of the biodiversity of alpine BSC algae is completely missing.

Advances in modern sequencing technologies, bioinformatics analysis tools, and environmental DNA cloning methods should allow for a movement in natural products discovery away from a random microbe screening approach to a more systematic sequence-based screening approach that will allow for the functional examination of gene clusters that remain hidden in the environment.

The success of these approaches is, partly, owing to the fact that modern sequence diversity has already been subjected to evolutionary selective forces and thus the diversity has already been deemed 'fit to survive'.

Nipponbare utilizing a deep sequencing approach.

Modern sequence data was trimmed to cover the same regions.

To improve the accuracy of TMH detection, we developed a machine-learning based predictor, MemBrain, which integrates a number of modern bioinformatics approaches including sequence representation by multiple sequence alignment matrix, the optimized evidence-theoretic K-nearest neighbor prediction algorithm, fusion of multiple prediction window sizes, and classification by dynamic threshold.

The conversion of ~93% of the assembled genome sequence to well-structured, oriented and annotated PMs has made potato more amenable to modern genomic/genotyping approaches, such as genotyping-by-sequencing (Uitdewilligen et al. 2013).

In addition, the genes of vertebrates retain detailed clues about their origins, and modern phylogenetic approaches can help piece together evolutionary sequences.