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While dormancy and resuscitation of rotifers had been observed by Leeuwenhoek himself in 1702, some of the earliest modern indications for a physiologically significant 'phenotypic heterogeneity' or differentiation of microbial cultures came in the 1940s.
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With a guest list of Silicon Valley luminaries and a party room redone in white — carpet, chairs, table and yes, mostly people — it was a very post-modern indication that MySpace, the social network owned by the News Corporation, was ready to engage with its brethren to the north by opening an office here.
In modern computational biology, there are two general approaches to drug repositioning: discovering new indications for an existing drug (drug-centric) and identifying effective drugs for a disease (disease-centric) [ 5].
High PTP1B inhibitory activity was predominantly associated with formulations that were classified as Jyokito in Kampo medicine and with a modern clinical indication of constipation.
We find CFC and SF6 concentrations well above solubility equilibrium with modern atmosphere, indicating local contamination, as well as indications of CFC degradation.
The dictionary contained probably more vowels than either Archaic Chinese or Modern Standard Chinese, another indication that the development of the Northern Chinese phonology did not pass the stage represented by Qieyun.
In addition, 21 of the 22 cherts analyzed had much more of the trace element cerium than do modern oceans, another indication that the microbes lived in an oxygen-poor sea.
In any case, if past sales of the "Call of Duty" franchise are any indication, "Modern Warfare 3" is all but certain to shatter records.
Lung cancer in a young Chinese girl who grew up in polluted urban environment and breast cancer in young women who kept their cell phones in their bras are stunning indications of modern risks where we cannot afford to wait for broader public impacts before reining in exposures.
Now with modern therapeutic regimes the indications of systemic treatment have been extended, whereas local tumor treatment is becoming rare.
Modern ECT has fewer indications and has been developed with the aim to reduce side effects [ 5].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com