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Modern computational systems biology aims at an overall description of the components, interactions, regulatory circuits, and metabolic fluxes in biological cells [1], [2].
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Considering the application aspects of high-performance calculations, one may conclude that the industrial codes yet cannot use perfectly all the resources that can be given by modern massive computational systems.
A full-scale search for RF shifts in all genes would require very powerful computational facilities that are not always available, although modern computer systems have made such search possible.
The computational effort required for a fragility analysis of structural systems can become excessive, far beyond the capability of modern computing systems, especially when dealing with real-world structures.
The search for significant epistasis (gene gene interactions) still poses as a computational challenge for modern day computing systems, due to the large number of hypotheses that have to be tested.
We present a simulation of the influence of a small sample tilt on the system resolution based on modern computational methods that enable simulation of the whole system including the parasitic fields, proper setting of centering deflectors and stigmators.
A critical aspect of applying modern computational solution methods to complex multiphysics systems of relevance to nuclear reactor modeling, is the assessment of the predictive capability of specific proposed mathematical models.
"The true pioneers of modern computational design, but without computers," Capozzo calls them.
As previously highlighted, in a modern complex computing system, the computational cores, memory banks, and communication bandwidth can be extremely heterogeneous.
Modern techniques such as the omics, coupled to bio-informatic and chemical computational systems, should guide the establishment of innovative technologies for agricultural practices.
In the light of the modern computational paradigm, it is no doubt that the intelligent manufacturing systems must be built on the basis of the Internet infrastructure.
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