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Histologically, 11% of the samples were well differentiated, 33% moderately well differentiated and 56% poorly differentiated.
We evaluated whether the previously observed association was homogeneous by category of stage (categorized as local or as regional or distant) and histologic grade (categorized as well differentiated or moderately well differentiated or as poorly differentiated or undifferentiated) of prostate tumor at diagnosis.
Histological features (Grade of differentiation); well: well differentiated; mod: moderately well differentiated; poor: poorly differentiated.
Since almost all patients with poorly differentiated carcinoma had metastases at presentation a poor differentiation seems to predict a worse prognosis compared to well and moderately well differentiated tumors.
All carcinomas were Dukes stage B and moderately well differentiated.
The majority of the patients without metastases had well or moderately well differentiated carcinoma.
Similar(39)
Several guidelines have indicated that in patients with well-differentiated or moderately well-differentiated prostate cancer (PCa), a staging bone scan may be omitted.
Generally, the tumor nodules exhibited a well- to moderately well-differentiated hepatocellular carcinoma, and a trabecular pattern was most frequently seen.
According to the most recent SEER data, the 5-year survival of patients with well or moderately well-differentiated tumours was: 82% for local spread.
There was no relationship between tumour volume and hypoxia in either the anaplastic sarcoma SaF or the poorly differentiated carcinoma CaNT and only a slight negative correlation in moderately well-differentiated carcinoma Rh.
Sensitivity to somatostatin analoguess, alone or in combination with interferon α have been used to treat well-differentiated and moderately well-differentiated endocrine tumours and to control the carcinoid syndrome (related to the inappropriate production of molecules with hormonal activity) that is often associated with these tumours (Kvols et al, 1986; Lamberts, 1999).
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