Sentence examples for moderately sensitized from inspiring English sources
WHI-P154 moderately sensitized ABCB1-overexpressing KB-C2 cells to its substrates whereas showed no sensitizing effect on ABCC1-, ABCC2 or ABCC10-mediated drug resistance.
In a series of 114 moderately sensitized DSA-positive patients, occurrence of de novo DSA (defined as absence of pre-transplant DSA) increasing at least threefold was monitored for a mean of 12.4 months [ 32]. rATG was given to 85 of the patients (mean total dose 4.98 mg/kg), and the IL-2RA induction agent basiliximab was given to 29 patients.
Moderately sensitized patients' wait times are close to non-sensitized patients' wait times.
Compared with anti-IL-2 therapy (basiliximab), induction with rATG in moderately sensitized KTR was associated with reduced incidence of de novo DSA and ABMR 92.
Although high c-MYC expression moderately sensitizes MB cells to DNA-damaging agents, we were unable to find evidence for this effect by analyzing neuroradiological imaging of postoperative residual tumors.
In summary, we report here that NFBD1 knockdown by lentivirus-mediated shRNA can inhibit cell growth, alter cell cycle progression, induce apoptosis and moderately sensitize CNE1 cells to radiation.
It has been demonstrated that inhibition of filamin-A moderately inhibited homologous recombinational DNA repair, sensitized cells to ionizing radiation and cisplatin, and prolonged the recovery of G2 arrest following irradiation [ 90].
We selected cell lines that were highly, moderately, or not susceptible to TRAIL-induced necroptosis when sensitized with CHX and compared this to HHT sensitization.
In Ren cells cocultured with TNF α, downregulation of cIAP1 and to a lesser extent XIAP and cIAP2 moderately increased sensitivity to AT-IAP; however, none of the other cell lines was sensitized to AT-IAP following siRNA-mediated IAP depletion, suggesting that high IAP expression is not responsible for resistance in these models.
In the same study, the cell lines had also been verified for cell surface expression of TRAIL receptors 1 and 2. Consistent with this previous study, the four tumor cell lines proved highly (Mz-ChA-1), moderately (HT-29, A818-4) or not (Pt45P1) susceptible to TRAIL-induced necroptosis when sensitized either with HHT or with CHX.
