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When the first ChIP was performed with anti-BES1 antibody and eluted chromatin samples were then immunoprecipitated with anti-RD26 or IgG control, significant enrichment of BES1/RD26 binding was detected in RD26OX plants, which is clearly reduced in rdQ mutant, and moderately reduced in BES1RNAi plants with two pairs of independent qPCR primers (Supplementary Fig. 9a,b).
Nevertheless, with the increase in vehicle velocity, CH duration is moderately reduced in DMCNF than in N-Hop.
Collateral vessel connections were moderately reduced in Il21r-deficient mice, and cerebral infarct volume increased 2.3-fold, suggesting that Il21r modulates both collateral vessel anatomy and innate neuroprotection.
Interestingly, we found that phosphorylation of the Akt consensus site T246 in PRAS40 is moderately reduced in Rictor knock down cells (data not shown).
Treatment with PTH markedly increased the number of differentiating osteoblasts, but the number of osteoclasts remained unchanged in bones engrafted with Hg myeloma cells and was moderately reduced in bones engrafted with primary myeloma cells.
It is clear from the data presented that H4K8ac levels are drastically reduced in brains expressing UAS-CBPi (Fig. 5C), moderately reduced in brains expressing UAS-Psni (Fig. 5F), and unaffected in brains expressing UAS-Ni (Fig. 5I).
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This expansion of the LGR5 compartment coincides with maintenance of crypt-like glandular structure (adenomas, and well and moderately differentiated adenocarcinomas), and is reduced in poorly differentiated CRC, where crypt-like glandular architecture is lost, accompanied by reduced epithelial terminal differentiation.
Lrig1 was detected in well and moderately differentiated tumours but was markedly reduced in poorly differentiated tumours (Fig. 4B D).
Both drugs severely inhibited DNA synthesis, cellular proliferation and Ras farnesylation in LoVo and moderately reduced them in Mahlavu and PLC/PRF/5 but not in KATO III.
MIBI images showed slightly reduced accumulation in the distal anterolateral to apical wall in the LV myocardium, while BMIPP images showed moderately reduced accumulation in the same region.
In the overall TTM study, LVEF on the first day was severely reduced (<30%) in 28% of patients and moderately reduced (30 50%) in 48%, with normal LVEF (>50%) in only 25% [ 21].
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weakly reduced in
comparatively reduced in
slightly reduced in
relatively reduced in
rather reduced in
moderately decreased in
somewhat reduced in
moderately lower in
moderately expressed in
moderately restricted in
moderately underrepresented in
moderately localized in
moderately conserved in
moderately wounded in
moderately affected in
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com