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Clinicaltrials.gov NCT00278070 Systemic therapy of metastatic cancers has moderately progressed over the last decade.
However, the mean CD4 count of 285 cells per μL (95% CI 269 301) of the HIV infected TB patients indicate that these were patients with only moderately progressed HIV infection reflecting that the study population was enrolled from outpatient clinic settings, not including severely ill patients requiring admission.
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In these particular patients we also have the RECIST-measurements confirming the stable nature of the tumours all through the treatment period with the possible exception of the first imaging time-point for patient 2, whose tumour progressed moderately between the baseline CT and the first SPECT, although in RECIST-terms the disease was still stable (less than 20% increase in tumour diameter).
It is possible that moderately differentiated portion was progressed different from well- and poorly differentiated portions, and poorly differentiated portion was expanded from well-differentiated portion with accumulation of allelic loss at 3p25.
We observed a considerable increase in C2CnT-L expression at the protein and mRNA levels as colorectal carcinomas progressed from well to moderately differentiated.
The clinician could predict that a patient would generally progress slowly, moderately, or rapidly over several years.
This defect may progress to a moderately severe hearing loss or deafness, between the first and second decades of life.
It is possible that some poorly or moderately differentiated tumours progress to moderately or well-differentiated tumour.
In moderately severe poisoning, paresthesia progresses to the arms and the legs, which also exhibit motor weakness.
All of us have been humbled by how quickly some EVD patients progress from being moderately stable to severely ill.
However, three randomly controlled trials of men with early stage, slow and moderately growing prostate cancer are in progress.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com