Sentence examples for moderately invasive from inspiring English sources

Up-regulation of uPAR significantly increased the invasiveness of the moderately invasive DU145 parental (DU145 P) cells through Matrigel, but this increased invasiveness was not seen in mice.

Both the highly invasive MDA-MB-231 cells [ 15], which over-express COX-2, and the moderately invasive MDA-MB-435 cells [ 21], which express moderate levels of COX-2, generated patterns that consisted of a translucent tubular network when plated on matrigel.

Membrane-type 1 overexpression by the moderately invasive OVCA429 and ES-2 cells caused a marked acceleration in their invasion.

The mode of invasion at the tumour host borderline was classified into three types (expansive, moderately invasive and markedly invasive), with a modification of criteria used by Umeda et al (1992).

Gene therapy for disorders of the central nervous system (CNS) is a moderately invasive method for delivering large molecules inside the blood brain barrier (BBB) as compared to mechanical devices such as pumps or reservoirs.

While we have known for almost 100 years that neural activity causes localized changes in blood flow, and researchers have more recently demonstrated that neural activity causes localized changes in blood oxygenation, the tools for measuring these signals have historically been highly invasive in animals and moderately invasive in humans.

Two strains (1261 and 1167) were moderately less invasive than L. monocytogenes EGDe, but none of the isolates demonstrated an invasion phenotype that was comparable to the PMSC1 L. monocytogenes isolate.

Histopathology revealed tumour 1 (Fig.  3g) as a 2.5 × 1.2 × 1 cm moderately differentiated (G2) invasive carcinoma NST, tumour 2 as a partially haemorrhagic, 2.5 × 2.3 × 2 cm moderately differentiated (G2) invasive carcinoma NST containing a postbioptic haemorrhagic cavity.

Final pathology demonstrated both lesions to be adenocarcinomas, which were moderately differentiated and invasive, without nodal disease.

Taken the results together, tumor budding represents an independent predictive biomarker with a good discrimination ability for both lymphogenous and haematogenous metastasis in moderately differentiated, subserosa-invasive CC.

Tumor budding could be used as a target to discriminate between different aggressive behavior patterns in subserosa-invasive, moderately differentiated CC.