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Metabolic work-up revealed elevated serum lactate (up to 8.5 mmol/L), moderately elevated plasma alanine (up to 630 μmol/L), slightly elevated ethylmalonic acid in urine (60 mmol/mol creatinine), and intermittently low plasma ketone bodies in preprandial state.
Transgenic mice with targeted overexpression of PAI-1 to gastric parietal cells using the H+/K+ ATPase β-subunit promoter (17), have moderately elevated plasma PAI-1, but in general, plasma concentrations are lower than those reported in other PAI-1 transgenic mice (25– 25).
In addition, moderately elevated plasma leptin levels unexpectedly exhibited a positive relation with FMD in overweight patients with T2D in this study.
The major finding of the present study is the lack of cardiac fibrosis in hypertensive cyp1a1 ren-2 TGR despite massively increased circulating prorenin levels and moderately elevated plasma aldosterone concentrations.
Although intima-media thickness of the carotid artery did not significantly differ between groups (lean, 1.06 ± 0.60 mm; overweight, 0.99 ± 0.45 mm; p = 0.456), it could be speculated that the overweight subjects in our study had less advanced atherosclerosis, and were thus able to respond to the vasodilator effect of moderately elevated plasma leptin levels at the time of FMD measurement.
Similar(55)
Workup revealed an elevated plasma renin activity and elevated plasma aldosterone.
Elevated plasma endothelial microparticle levels have been found to be elevated in women with preeclampsia.
Elevated plasma glucose levels in pregnancy increase adverse pregnancy outcomes.
Elevated plasma HBP levels are associated with increased plasma lactate and maximum dose of norepinephrine at day 1 after admission.
Elevated plasma IL-6 and -8 levels are predictive of outcome in patients with ALI [44].
Conclusions: Patients with overt DIC do not have elevated plasma levels of nucleosomes.
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Justyna Jupowicz-Kozak
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