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The findings suggest that hypertension patients could benefit from aggressively treating even moderately elevated cholesterol levels.
The study, published in The American Journal of Clinical Nutrition, involved feeding 34 college students with moderately elevated cholesterol levels a lunch of ground beef every day for a month.
In this study, 4,444 patients with angina pectoris or previous myocardial infarction, and moderately elevated cholesterol levels (5.5 8.0 mM), received either simvastatin or placebo and were followed up for a mean of 5.4 years.
The Long-Term Intervention with Pravastatin in Ischaemic Disease (LIPID) trial included 3514 patients aged 65 and 75 years who had a prior infarction or unstable angina in addition to average or moderately elevated cholesterol levels (155 271 mg/dL) (Hunt et al 2001).
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Subjects had an increased cardiovascular risk with moderately increased heart score, elevated cholesterol levels, slightly increased body mass index, and mild systolic hypertension.
We question the "speculation" of Sun et al. because there are now substantial findings that consistently place the juxtaposition of moderately elevated GGT levels before the onset of other "traditional risk factors" such as obesity, insulin resistance, elevated cholesterol, and glucose measurements.
Should a middle-age woman with mildly elevated cholesterol take a statin, for example?
Most had slightly but not dangerously elevated cholesterol levels.
In any event, the benefit is likely to accrue mostly for people who have elevated cholesterol to begin with.
(Elsewhere, the book warns that a popular brand of lip balm will cause elevated cholesterol levels if eaten).
Should older adults take statins if they have elevated cholesterol but no evidence of heart disease?
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