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For example, Figure 5 shows that a mildly contagious disease like SARS may be thwarted by partial coverage (≈75%) with a moderately efficacious vaccine (≈60% vaccine efficacy).
Memantine has been shown to be moderately efficacious in the treatment of moderate to severe Alzheimer's disease.
Conclusions: Zinc-ORS was moderately efficacious in reducing the severity of acute diarrhea without increasing vomiting or reducing ORS intake.
Although both were moderately efficacious, neither could induce the durable, robust humoral and cellular immunity commonly seen in HCMV seropositive subjects.
Although both were moderately efficacious, neither could induce the durable, robust humoral and cellular immunity commonly seen in CMV seropositive subjects.
In monotherapy two treatment cycles were moderately efficacious in the Lu7336 model but showed good anti-tumor activity in the KRAS mutant Lu7187 model (26% and 80% tumor growth inhibition, respectively).
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A meta-analysis of 23 randomized controlled trials suggests that probiotics are safe and moderately effective at preventing CDI, although additional trials need to be conducted to identify probiotic mixtures that are most efficacious in preventing CDI.
Herd immunity effects can be achieved with even moderately effective (>20%) malaria vaccines (either PEV or BSV) when deployed through mass campaigns targeting all age-groups as well as EPI, and especially if combined with highly efficacious transmission-blocking components.
Despite the availability since the 1980′s of an inexpensive, efficacious, and moderately well-tolerated therapy, that can cure 90% of cases, tuberculosis (TB) continues to be a major worldwide health problem, with 8.6 million new cases and 1.3 million deaths in 2012 [ 1].
For an allosteric effector to be a safe and effective treatment for SCD, the compound should be highly specific for hemoglobin and moderately increase the oxygen affinity without causing hemolysis at efficacious doses.
It proved efficacious in protection against H3 virus subtype and moderately against other subtypes, for example, H5, H7, H2, and H1.
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CEO of Professional Science Editing for Scientists @ prosciediting.com