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Exact(15)
The equivalents of residues F338 and D339 are moderately conserved in the MBOAT family (FD in Hhat and GUP1, FN in LPAT5, and WN in the other family members).
The positions with highest FC, 2.57 and 3.32, are only moderately conserved in G0 (28% Cys and 31% Gln, respectively) whereas they are highly conserved in G1 and G2, respectively.
The sites showing significant signal for positive selection (Table 3, test 6) are moderately conserved in the pfam alignment for the matK amino terminal region (positions 224 and 277 in the complete alignment of pfam01824), but no function has been hypothesized for this portion of the matK protein.
Aspartate 299 is moderately conserved in bacterial ProRSs.
In contrast, the FRQ/FRH interaction domain (FFD) is only moderately conserved in P. confluens.
The LBD is highly conserved in structure, and moderately conserved in sequence.
Similar(45)
This variant altered a moderately conserved AA in the ND6 polypeptide.
As mouse and rat have an evolutionary distance (divergence time) at least 4 times that of human and chimpanzee [ 37], these results indicate that hits of these queries have moderately conserved distributions in mammalian genomes.
In a final analysis of the networks, we compared proteins that are highly conserved across species (present in four or five of our test species) to proteins that are only moderately conserved (present in two or three of our test species) or are unique to their species.
The SMART-derived consensus sequence (indicated on the top of the multiple sequence alignment, Fig. 1) for SCP/TAPS domains indicates five of these seven invariant residues are conserved across phyla (found in 80% or more of superfamily members) and the other two are moderately conserved (found in 50 79% or more of superfamily members).
Our analysis also reveals two further moderately conserved basic residues in the carboxy-terminal half of Vps25, arginine-126 and arginine-183, which are exposed on the surface of yeast Vps25p [ 20].
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somewhat conserved in
quite conserved in
moderately expressed in
moderately restricted in
moderately underrepresented in
moderately reduced in
moderately localized in
moderately wounded in
moderately correlated in
moderately decreased in
moderately increased in
moderately induced in
moderately supported in
moderately affected in
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