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A virtual screening approach using various in silico methodologies led to the discovery of 2- m-tolylamino -7,8-dihydroquinazolin-5 6H -one (1) as a moderately active negative allosteric modulator (NAM) of the metabotropic glutamate receptor subtype 5 (mGluR5) showing high selectivity against the subtype mGluR1.
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The growth inhibition was moderately active against gram-negative bacteria Escherichia coli (8.5 mm) and Klebsiella (0 mm).
If you are moderately active (moderate exercise/sports 3-5 days/week) : BMR x 1.55.
An extract was considered active on the adult female worm if there was a 90%% or greater inhibition of formazan formation compared to the negative controls; or moderately active if the inhibition was 50 89 %.
An extract was considered active on the adult female worm if there was a 90%% or greater inhibition of formazan formation compared to the negative controls; or moderately active if the inhibition was 50 - 89%.
An extract was considered active if there was a 90% or greater inhibition of formazan formation compared to the negative controls; or moderately active if the inhibition was 50 - 89%.
A validated four-point physical activity index was used to categorise participants according to activity level (active, moderately active, moderately inactive, inactive) [ 19].
Chloramphenicol [43] Human 2,000 Posterior NA NA NA 24 Gram-negative bacteria, Rickettsia, Borellia recurrentis; moderately active against Gram-positive bacteria and Mycobacterium tuberculosis 14.
In order to calculate your baseline calorie requirements, you indicate your activity level: sedentary, lightly active, moderately active, or very active.
Total MET-hours/week in walking, cycling and sports were computed to derive a four-category recreational physical activity index: inactive, moderately inactive, moderately active, active.
Physical activity level was indexed into five categories (inactive, moderately inactive, moderately active, active or unknown) based on occupational and recreational activities [22].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com