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It has been reported that mild-to-moderated hepatic dysfunction in patients with colorectal cancer liver metastases did not significantly affect capecitabine pharmacokinetics [ 15].
Hepatic dysfunction, either hepatitis cytolysis or hepatic insufficiency were found in 13 (21%) and 4 (6%) patients.
Hepatic dysfunction.
Dose reduction may be necessary in patients with hepatic dysfunction.
Ligustrazine inhibited these changes and alleviated burn-mediated hepatic dysfunction.
Burn results in hepatic dysfunction and increased hepatic NF-κB activity, elevated liver wet/dry ratio and hepatic MPO activity.
There was also no association of lactate on admission and hepatic dysfunction as assessed by the hepatic SOFA subscore.
We also needed to take special care for selecting anesthetics because the patient had hepatic dysfunction.
They showed no differences in the rate of hepatic dysfunction or mesenteric ischemia [28].
He was being administered ursodeoxycholic acid orally for treatment of his hepatic dysfunction.
Jaundice and cholestatic hepatic dysfunction are frequent findings in critically ill patients associated with increased mortality.
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