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For 30 years, Dr. Marlatt was director of the Addictive Behaviors Research Center, an arm of the University of Washington in Seattle that nurtured a movement among therapists holding that addiction treatment should take a more moderated approach than is common in traditional 12-step programs calling for complete abstinence, like that of Alcoholics Anonymous.
Robert Harms, chairman of North Dakota's Republican party and an energy industry consultant, told Reuters on Thursday that a "moderated approach" was needed amid an energy boom that has transformed the local economy, but created safety concerns.
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To further select for significantly differentially methylated CpG sites we used a false discovery (FDR) approach using limma moderated T-test, which is based on an empirical Bayes moderation approach [62].
This was based on the hierarchical moderated regression approach [ 38].
And he can thank the freak show that is Donald Trump's Republican party for restoring his stature as a unifying, national leader with a moderated and mature approach to a complex and unstable world.
A moderated hierarchical regression approach is used to analyze the models, which are further explored by firm size and industry type.
LIMMA uses a moderated t-test approach to identify differentially expressed genes [10].
However, instead of the ANOVA analysis used in the above study, the moderated t-test approach of LIMMA implemented in Bioconductor [11] was used to identify differentially expressed genes.
Limma is a moderated T-statistic approach that detects differentially expressed genes between test groups, given the natural variance within these test groups, adjusted for multiple testing [ 31, 33- 35].
Differential expression between cytokine-treated and untreated control cells was evaluated using the empirical Bayes approach and moderated t-statistics as implemented in Bioconductor's limma package [ 71].
For the remaining 18793 genes, raw p-values were calculated based upon the empirical Bayes approach and moderated t-statistics implemented in Bioconductor's limma package [ 71].
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