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After the latter normalization we found a moderate, yet significant, elevation of α1-ACT in CSF samples of sCJD patients (46%, p<0.001, Table 2).
In contrast, absolute horn loss exhibited a moderate, yet significant, increase with adult size (Fabs = 11.25; p = 0.0016).
Therefore, binding of HCAb2 to HSP90 could inhibit invasiveness of MDA-MB-231 cells at a moderate yet significant level.
Taking these data together, we conclude that PINK1 deficiency results in moderate yet significant alterations in mitochondrial ultrastructure.
We observed a moderate, yet significant (r = 0.42, P < 0.001) correlation between plant height and Septoria tritici blotch severity (Additional file 3: Figure S3).
In addition, hypoxia led to a moderate yet significant increase (2-fold) in the expression of PTGS2 (COX2), suggesting activation of the arachidonic acid/COX2 pathway.
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Finally, most methods are limited in their ability to capture orientation dispersion, resulting in low to moderate, yet statistically significant, correlation with histologically-derived dispersion with both HARDI and NODDI methodologies.
As opposed to IL-17A, even a single systemic administration of 3 µg of IL-23 (intraperitoneal injection) on the day of infection provided a moderate, yet statistically significant, benefit when compared to the control PBS treatment.
The R values were each <0.3, suggesting a moderate, yet highly significant, association between Fop and RPM.
In summary, established rho0 cells display a high rate of nuclear genome instability (mostly chromosome breaks) with two modes: very high CIN in slow-growing rho0 and a more moderate yet highly significant increase in faster growing rho0 cells.
At the conclusion of the treatment, Daniel realized notable 6-month changes, including moderate yet clinically significant improvement in HbA1c (drop of 0.9 from baseline) and marked reductions in depression (PHQ-9 score improved 14 points) and diabetes distress (PAID score improved 37.5 points).
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