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Altogether, these results indicated that hypertonicity triggered a rapid cell cycle arrest in both wild-type and NFAT5−/− T cells, but while the former induced osmoprotective gene products and resumed proliferation with only a moderate viability loss, NFAT5−/− cells had poorer viability, and those surviving exhibited cell cycle defects.
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In the present study, in vitro pollen germination studies showed moderate pollen viability (64%).
As with our data using the new Dcas1 allele, homozygous deletion of Dcas in conjunction with integrins had moderate effect on viability of adult flies, although our work for the first time demonstrates an interaction between Dcas and if and mew, and also between Dcas and Src, in regulation of wing development.
Moderate decreases in viability were observed in CnOb cells treated with at 50 μM ritanserin (p < 0.01).
SOX11-deficient cell populations that showed moderate decreases in viability also exhibited moderate increases in cleaved caspase-3 levels and decreased percentages of cells in G2/M phase, whereas no change in the G2/M percentage was observed in the least viable SOX11-deficient cell population that displayed the highest increase in cleaved caspase-3 levels.
Corn fodder at a net cost of $26 Mg−1 feedstock showed a moderate potential for economic viability compared to forest residue.
MTT and resazurin assays showed a moderate reduction in cell viability related to increased DNA concentration in the DNA-PFs.
The effect of compounds 14aa and 14aa-OH are accompanied by a moderate loss of cell viability.
Comparatively, for the high revenue scenario ($80 Mg−1CO2ee), forest residue continued to be a poor economical option with net costs of $9 Mg−1 biomass, whereas corn fodder showed gains of $26 Mg−1, indicating a moderate potential for economic viability (Fig. 10).
Pharmacological inhibition of IMPDH induced a moderate reduction of cell viability and a strong decrease of cell proliferation, but no increase in chemosensitivity.
Following ritanserin treatment, a moderate decrease in COS viability was found at 6.25 μM (p < 0.01), with marked decreases observed at 12.5, 25.0, and 50.0 μM (p < 0.01).
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