Sentence examples for moderate variant from inspiring English sources

Southern rebel commanders have aggressively marketed themselves to potential Western patrons as the "moderate" variant favored by Washington.

At one extreme we find the radical "unifiers" (who take events to be as coarse-grained as ordinary objects [Quine 1985; Lemmon 1967]), at the other the radical "multipliers" (who take events to be as fine-grained as facts [Kim 1966]), and in between several moderate variants [Davidson 1969; Thalberg 1971; Thomson 1971; Brand 1977; Cleland 1991].

Although each of these alternative methodological approaches features more moderate variants that reserve a legitimate place for moral principles and even for some kinds of theory, their stronger anti-theory incarnations unite in rejecting any justificatory role either for high moral theory or mid-level moral principles.

The fraction of moderate variants ranged from 0.93 to 1.5% according to the accessions and the low effect from 0.80 to 1.3%.

The SNPs on the iCOGS array were nominated by consortium members, and were: SNPs identified by meta-analysis of prior GWAS; SNPs for fine mapping of known susceptibility loci; candidate functional variants and moderate penetrance variants; and SNPs related to other traits, including other cancers and medical conditions.

3– 5 It may be a moderate risk variant for systemic sclerosis, but it is not associated with other autoimmune diseases.

For instance, inherited breast cancer predisposition is currently thought to result from rare high penetrance mutations in high risk families, or multiplicative effects of moderate penetrance variants or common low risk variants in the population [ 1, 2].

The number of coding variants correlates with high or moderate impact variants as illustrated in Fig. 2. The plot illustrates the correlation using a Lowess smoothing function, and is annotated by self-reported race.

Inherited alterations driving neurodevelopmental disorders are complex, including not only de novo mutations and common, low-risk polymorphisms but also high or moderate risk variants including copy number variation.

Genetic factors are also involved in the etiology of breast cancer, including rare high-risk mutations (BRCA1 and BRCA2), more moderate susceptibility variants (CHEK2, ATM) and several as yet unidentified common susceptibility variants associated with low to moderate increased risk [ 4, 5].

Therefore, detection of such haplotypes can lead to the identification of rare or moderate penetrance variants behind disease susceptibility.