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Nutmeg oil had moderate toxicity and ylang ylang oil was the least toxic.
Based on these, a similar response would be expected for P. putida F1 exposure to benzoate considering its moderate toxicity and its structural similarities to phenylphenol.
The group reported moderate toxicity and that the measured AUC values did not reach the desired target AUC.
The low level of Tau overexpression from our 68A insertions results in moderate toxicity and provides a baseline to investigate factors that increase toxicity.
This regimen had moderate toxicity, and resulted in a median progression-free survival (PFS) of 14.2 months and median OS of 21.1 months.
The regimen used in this phase II trial produced moderate toxicity and is comparable with reported literature on neoadjuvant chemoradiation regimens including paclitaxel.
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Nine patients died in the moderate toxicity group and four patients died in the high toxicity group (P > 0.05).
Grading of acute radiation morbidity, according to the VROTG scheme [ 13] (additional file 1), assessed by the clinician, revealed moderate toxicity with mean and median scores of 1.6 and 1.
Another independent variable was Use of Pesticides Types Ib and II, classified by the WHO 20 as being of high toxicity and moderate toxicity, respectively.
Patients were divided into three groups based on the level of skin toxicity reported: no/mild toxicity (grade 0 or 1), moderate toxicity (grade 2) and severe toxicity (grade 3+).
A phase II study in 41 patients with advanced STS showed limited activity and moderate toxicity as a single agent, with two patients experiencing a PR and a median time to progression of 2 months.
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