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Preoperative laboratory findings confirmed an usual compensatory mechanism for chronic but moderate tissue hypoxia.
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These included (a) severe global tissue hypoxia (lactate of greater than or equal to 4 mmol/L and ScvO2 of less than 70%), (b) moderate global tissue hypoxia (lactate of greater than or equal to 2 mmol/L and ScvO2 of less than 70%), and (c) resolved global tissue hypoxia (lactate of less than or equal to 4 mmol/L and ScvO2 of greater than or equal to 70%) [ 38].
Adipose tissue hypoxia.
A normal ScvO2 therefore does not exclude tissue hypoxia.
Conclusions: Patients with septic shock show peripheral tissue hypoxia.
Tissue hypoxia was monitored by non-invasive transcutaneous spectroscopy (NIRS).
Finally, the reduction in tissue hypoxia should improve organ function.
ScvO2 failed to predict the presence of global tissue hypoxia.
As such, it inhibits the release of oxygen from hemoglobin to peripheral tissues, causing tissue hypoxia.
Direct tissue oximetry in hyperdynamic sepsis failed to show tissue hypoxia.
Tissue hypoxia is a key trigger of organ dysfunction.
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