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Baseline physical fitness that appeared to moderate the intervention effects on testosterone and SHBG levels and age seemed to moderate the intervention effects on testosterone levels.
Additional secondary outcome measures include behavioral and psychosocial factors that might moderate the intervention effect.
For testosterone, intervention effects were comparable across dichotomized subgroups; however, fitness (continuous, p = 0.035) and age (continuous, p = 0.038) appeared to moderate the intervention effect in general linear models.
Logistic and linear regression analyses will be performed to identify if baseline variables, such as depression, oral health knowledge, and dental anxiety, health fatalism, predict mother or child outcomes, and whether any of these variables moderate the intervention effect.
In the analysis, we will adjust for other patient characteristics that may moderate the intervention effect or reduce unexplained variability including gender, age, baseline function score, BMI, depression, anxiety, or social support.
Similar(55)
In addition, the study analyzed whether the secondary outcomes moderated the intervention effect on depressive symptoms.
None of the secondary outcome variables moderated the intervention effect on depressive symptoms.
Finally, none of the outcome variables moderated the intervention effect on depressive symptoms.
Course attendance and the home practice of mindfulness moderated the intervention effects on mental distress but did not affect subjective well-being.
There were no significant changes in overall behavior competence (p = 0.11) or physical functioning (p = 0.30) by stage of dementia (mild vs. moderate) in the intervention group, counter to the hypothesis.
The quality of evidence for preterm birth and low birth weight is moderate, and the intervention has a weak recommendation for preventing preterm birth.
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