After controlling for other factors that may influence FP use, an increased ANC/PNC intensity score was significantly associated with a moderate but significant increase in the likelihood of modern FP use after a woman's last birth (hazard ratio=1.09; p<.05).
During vacuum annealing, all coatings examined exhibited structural stability to temperatures in excess of 900 °C, and revealed a moderate, but significant, increase in hardness.
Interestingly, a treatment with this ER-ligand, caused moderate but significant increase of CYP1A mRNA expression (about 2.5-fold; P < 0.05).
Although anandamide, at a concentration of 10 μM had a moderate vasoconstrictor effect on meningeal blood vessels, following the administration of AM 251 prior to the application of anandamide, a moderate but significant increase in meningeal blood flow was recorded.
Conversely, MVECs transduced with WT calpain-I exhibited a moderate but significant increase in activity (Fig. 2A).
The mild heat-shock treatment induced the moderate but significant increase of GFP signals in Pmtl-1 GFP Pmtl-1 GFP:GFP trandgenic strains.
In line with this hypothesis, sst2A receptor stimulation induced a moderate but significant increase of the axonal length of hippocampal neurons in culture.
Indeed, until now only a recent large meta-analysis including tens of thousands of patients has been able to detect a moderate but significant increase in the risk of coronary disease associated with either the Factor V Leiden mutation or the prothrombin 20210A variant [8].
In comparison, relative Top-FLASH activity in the SW480 and HCT116 colon cancer cell lines was greater than that seen in any PDA cell lines (>6 Top/Fop ratio and >10 Top/Fop ratio respectively, data not shown), indicating that the majority of PDA cell lines show a moderate, but significant increase in Wnt activity.
A moderate but significant increase of RGS5 abundance was also observed 3 days upon induction of arteriogenesis (Supplementary Fig S1).
