Sentence examples for moderate sequencing depth from inspiring English sources

Indeed, our study demonstrates that at the moderate sequencing depth employed, there were more assignable sequencing tags to protein-coding regions utilizing cDNA compared to genomic DNA, which consequently increased our ability to detect microbial taxa.

The ambition of cloneHD is to automate some of the steps of this analysis, while being routinely applicable to whole-cancer-genome data at moderate sequencing depth.

Given our moderate sequencing depth in the placental tissues, it is possible that additional ESRP1 target exons with differential splicing in amnion were missed by RNA-Seq.

It should be noted that given the moderate sequencing depth of 50-83 million reads per tissue, this analysis is expected to have an appreciable level of false negatives.

The recently proposed d2 S measure performs the best in all scenarios and the optimal tuple size for it is between 5 and 9, for NGS data with moderate sequencing depth of about 10,000 sequences of 200nt.

The optimal choice of tuple size depends on sequencing depth, but it is quite robust within a range of choices for moderate sequencing depths.

We can see that the optimal tuple sizes, at lower or moderate sequencing depths, are between 4 and 7, and this range also gives the smallest standard deviation although the standard deviation is, in general, very small.

However, we believe that the estimation of isoform-specific expression is a very difficult task, especially for genes with strongly overlapping isoforms and at moderate sequencing depths, and accordingly any isoform-specific expression estimates inevitably are associated with a certain degree of uncertainty.

These pools were subsequently mapped back to their corresponding reference sequences using commonly applied alignment software and at a range of ultra-low to moderate sequencing coverage depths (0.1×, 0.5×, 1×, 2×, 4×, 8× and 16×).

While adding this extra filtering step after variation detection can reduce FPs caused by false alignments, it is at the cost of a significant loss in sensitivity, especially when the sequencing depth was moderate.

We can also see that the standard deviation of the parsimony score among the 100 repeated experiments at each sequencing depth is quite moderate and stable with different choices of k, and deeper sequencing will decrease the standard deviation of the parsimony scores, as expected.