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This moderate risk reduction has to be weighed against toxicity.
This clinical trial showed a statistically significant benefit of the combination of high-dose AOX vitamins and zinc, providing a moderate risk reduction of developing advanced AMD over a median of 6.3 years of follow-up in those at high risk of developing advanced AMD.
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Only those women at low or moderate risk showed significant reductions in cancer worry and perceived risk of breast cancer.
Overall results showed a significant risk reduction (moderate to high heterogeneity).
In this systematic review of 7150 participants with established CHD or CAD comparing reduced and/or modified fat diets versus control diets, no significant risk reduction (moderate quality of evidence) for all-cause mortality, cardiovascular mortality, cardiovascular events and myocardial infarction could be observed.
The independent variable within the first level will be the magnitude of the absolute risk reduction (high, moderate and low).
Although grid laser photocoagulation can result in a 50% risk reduction of moderate visual loss, the treatment is limited to vision stabilization or minimal mean improvement in vision.
As the model simulated only clinical vertebral fractures, the risk reduction of moderate and severe vertebral fractures in postmenopausal women was used as a proxy for clinical vertebral fractures.
These results resemble the values for moderate risk and mirror the incremental reduction in sensitivity with increased cut-point score selected for the sensitivity/specificity analysis observed using the CANRISK questionnaire [ 15].> -wrap-foot> R = 0.235, Adjusted R = .224.224
For low risk and moderate risk women, other than a significant reduction following counselling for low risk women (t(23)=2.81, P<0.01), perceptions remain stable.
However, the view that physical activity has to be moderate to vigorous to achieve cardiovascular risk reduction has been questioned [ 11].
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