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Ms. Loadholt, who has been at the bureau for 5 of her 27 years of experience, oversees a staff that teaches quality-of-life skills to underprivileged individuals, high school seniors and older, with developmental disabilities ranging from mild to moderate retardation.
Participants with mild retardation performed better than their counterparts with moderate retardation on the simulated tasks and in the community settings.
Forty individuals participated in the assessment and training activities of this study, including 20 participants with mild retardation and 20 individuals with moderate retardation.
Participants with mild retardation were more successful in generalizing from the simulated instructional experiences to the community settings than were their counterparts with moderate retardation.
In this study of simulated instruction and/or community training of four functional living tasks was compared across groups of adolescents and young adults with mild and moderate retardation.
Moreover, some researchers say, the observation that MCPH patients can speak, and that they suffer at most from moderate retardation, indicates that the ASPM gene is not key to intelligence itself--whether or not it might have played a role in scaling up the hominid brain to modern dimensions.
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* Data expressed as mean score ± SD † Fisher's exact test p-value ‡ Student's t-test p-value § Wilcoxon rank sum test exact p-value With respect to the General IQ, while 40.0% (n = 6) of patients without neuroimaging abnormalities were observed to have scores indicative of moderate mental retardation, none had severe mental retardation.
Neurological signs of these three patients ranged from a mild mental handicap (SLS-2) over severe autism in combination with moderate mental retardation (SLS-3) to severe mental retardation associated with ataxia and a MTS (CORS-1).
This study examined fatigue profile during intermittent exercise in 10 men with mild to moderate mental retardation (MR) and 10 men without mental retardation (C).
Also, three nuclear families with GLUT1 DS were reported to date, in which the phenotype between family members varied from intractable epileptic seizures with moderate mental retardation to controllable epileptic seizures with mild mental retardation (Brockmann et al., 2001; Ho et al., 2001; Klepper et al., 2001 b ).
Estimates were therefore derived from a population-based study using data from the state of California [ 47], which calculated a LE of 65 years for children with mild or moderate mental retardation who did not have Down syndrome, and of 51 years for those with severe mental retardation.
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