Our results support the findings of the American Academy of Orthopaedic Surgeons [36], which gave acromioplasty a "moderate" recommendation for the treatment of rotator cuff disease.
Graded recommendations were considered as A: Strong recommendation, B: Moderate recommendation, C: Weak recommendation or D: Insufficient evidence to make a specific recommendation.
In December 2009, the DHHS recommended therapy for all patients with CD4 cell counts in the 350 to 500 cells/μL range, although the group was divided as to whether this was a "strong" or "moderate" recommendation.
The results in the present study show that primary care physicians' exercise recommendation levels for CKD patients were limited because their rate of positive exercise recommendations (high recommendation: 5.4% + moderate recommendation: 30.9%) was < 40% and their rate of negative exercise recommendations was > 50% (low recommendation: 44.1% + no recommendation: 15.8%) for such patients.
Each recommendation was thus allocated a final level of evidence which determined its wording: (i) we recommend (or we do not recommend) for a strong recommendation, (ii) we strongly suggest (or we strongly do not suggest) for a moderate recommendation (iii) we suggest (or we do not suggest) for a weak recommendation (Additional file 1, Table S2).
Furthermore, multivariable linear regression analysis showed among the CKD primary care physicians who had high and moderate exercise recommendations for CKD patients, exercise recommendations frequency was associated with their own exercise frequency (p < 0.01) but not exercise intensity (Table 7, Figure 2).
There was even louder criticism when a broader review of banking, led by Sir John Vickers, published moderate interim recommendations in April.
The primary intent of the BETA Trial is to determine whether a higher volume of aerobic exercise is likely to provide further reductions in breast cancer risk compared to the current moderate volume recommendations.
Also the 2010 guidelines on the use of therapeutic apheresis in clinical practice [ 27] list TPE as a 2B (weak recommendation, moderate quality evidence) recommendation in the treatment of sepsis, making the individual clinical and laboratory course of patients along with the available resources the foundation for TPE prescription in sepsis.
