Meta-analyses of the moderate-quality RCTs found that acupressure as monotherapy fared marginally better than sham control.
Three studies, including two moderate-quality RCTs and one low-quality RCT, consistently reported that case management interventions had significant effects on improving clients' unmet service needs [ 32, 34, 36].
One moderate-quality RCT reported no significant intervention-control group differences in the number of ADL or IADL disabilities during six-month and 12-month follow-up periods respectively [ 38].
The other five studies all (including one low-quality RCT, one moderate-quality RCT, two low-quality quasi-experimental studies and one low-quality retrospective cohort study) reported no significant intervention-control group differences in client mortality of their different study periods [ 34, 38, 40, 41, 43].
Of the two studies examining client medical conditions, one low-quality quasi-experimental study reported less pain and dyspnoea among participants in the intervention group during the 12-month follow-up period [ 41], while the other moderate-quality RCT showed no significant intervention-control group differences in client health status during six-month, 12-month and 18-month study periods [ 38].
One moderate-quality RCT reported that participants in the intervention group were significantly less likely to die or be admitted to residential care during the 18-month study period [ 39], while another low-quality quasi-experimental study found that the intervention group increased longevity significantly during the first and second years [ 44].
However, Buljac-Samardzic 13 concluded that the majority of studies reviewed were of low-level to moderate-level quality even though eight of the reviewed team-training studies were categorised as high or moderate quality (ie, RCT or high-quality pre-post study).
Interpreting results about possible beneficial effects of immediate statins therapy in statin-naïve patients following aSAH is limited by small sample sizes and low to moderate quality of available RCTs and very low quality for observational studies.
There is moderate quality evidence (2 RCTs, n = 229; limitations in imprecision) that mPrT is no more effective compared to inactive controls at long-term follow up.
