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FPIR demonstrated significant but moderate prognostic value with an AUC value of 0.61 (95% CI 0.55 0.67), as did FPIR/HOMA-IR with the same AUC value.
PTX3 upon admission demonstrated significant but moderate prognostic value for prediction of 1-year mortality but not for 30-day mortality.
The actual values of PTX3 and BNP upon hospital admission were not significant predictors of short-term mortality and had only a moderate prognostic value for 1-year mortality.
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Thus, such transient enzyme elevations, particularly those that are low or moderate, have little prognostic value.
The cut-off was guided by the Nottingham Prognostic Index (NPI) value, with which the value of the moderate prognostic group was used as the dividing line at the start of the test.
Although resting BP indices are clinically important, hemodynamic responses to moderate exercise may have stronger prognostic value in terms of cardiovascular risk [ 14], suggesting that pathophysiological insight may be gained from exercise hemodynamics beyond that of resting conditions.
Our data confirm the independent prognostic value of hyponatremia, even moderate, in patients with acute decompensated HF.
Cohort studies including patients with moderate or severe TBI having evaluated the prognostic value of UCHL-1 according to mortality or the Glasgow Outcome Scale (GOS) were considered.
Having an excellent prognostic value in spite of moderate interobserver agreement with the Gold Standard is likely due to the modest specific contribution of 'diagnosis' to the overall APACHE IV calculation which also takes into account multiple physiological and laboratory values.
Our objective was to systematically review the prognostic value of NSE levels following moderate or severe TBI.
This observation is consistent with the notion that total EGFR levels serve as a moderate prognostic indicator in breast cancer patients and thus suggests a novel prognostic value of nuclear EGFR in these patients.
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