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Therefore, a non-invasive and inexpensive tool to predict the risk of subclinical or silent atherosclerosis with more than moderate predictive ability is required for identifying individuals at high-risk of CVE.
Many of the existing approaches have moderate predictive ability, which may result, in part, from not considering potentially meaningful changes in spending over time.
However, most of the CBC parameters demonstrated poor to moderate predictive ability for 7-day in-hospital mortality in adult trauma patients.
It has been proposed that some genes may have moderate predictive ability in many patients, while some may be "master genes" with high predictive ability in as yet undefined subsets of patients [13].
Receiver operating curves (ROC) of pGSN levels and APACHE III scores with 28-day mortality as outcome is shown in Figure 3. pGSN levels showed moderate predictive ability with an area under the curve of 0.86 (p = 0.01).
We show that each evidence feature has a moderate predictive ability, and the area under the receive operating characteristic curve (AUC) ranges from 0.57 to 0.88.
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We found that ZΔ G alone had moderate predictive power and CAI had substantial predictive power.
To determine the association between these gene signatures and the expression of all detectable miRNAs, we consider the summary score for each signature as the dependent variable of a linear model consisting of all miRNAs showing at least moderate univariate predictive ability for the summary score (Fig. 1a).
Traditional additive QTL models nevertheless provide only moderate prediction ability.
Furthermore, we used a standard method to identify the predictor variables and derived a simple to follow rule with moderate predictive and discriminative ability.
A recent systematic review examined the predictive value of the rule in elderly inpatients at risk of falls and found that at a score ≥2 points, the STRATIFY rule had only limited predictive ability with moderate summary estimates of sensitivity (0.67, 95% CI 0.52 – 0.80) and specificity (0.57, 95% CI 0.45 – 0.69) [ 6].
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