Sentence examples for moderate pathology from inspiring English sources

Axial score was higher in the group with severe Lewy pathology when compared to the groups with absent (0) or moderate pathology (p<0.01) (figure 3B), and axial score positively correlated with the Lewy pathology score (p = 0.004).

When PS+ patients were further stratified into subgroups with moderate and severe pathology, there was a highly significant difference in NF-IR between PS+ patients with severe pathology and the control group (p<0.01), and furthermore significant differences were apparent between the severe pathology group and those with absent (0) and moderate pathology (p<0.05) (figure 2D).

"-" = no pathology, "+" = mild pathology, "++" = moderate pathology, "+++" = strong pathology.

All cases showed marked loss of neurons in the substantia nigra pars compacta exceeding 60%, whereas moderate pathology occurred in the caudate and putamen.

> -wrap-foot> > -wrap-foot> Table  4 shows the sensitivity, specificity, positive, and negative predictive values of PHHE to detect at least moderate pathology.

Although the dentate gyrus does not have direct projection to substantia nigra, regions connecting with dentate gyrus (i.e., hippocampal CA1, CA3, entorhinal cortex, fimbria, fornix and hippocampal commissure) also showed moderate pathology (Table 1).

Whilst there was moderate FUS pathology in the form of NCIs and GCIs in the spinal cord, the twelfth nerve nucleus, and mild pathology for FUS in the motor cortex, there was marked CD68 positivity in the motor cortex indicating increased microglial activity and associated with neuronal loss in this region.

Consistent with our previous findings [20], [21], sham-treated pR5 mice presented with a moderate tau pathology, including phosphorylation at the S202/T205 epitope (AT8), whereas other more pathogenic sites, such as S422 (PS422) revealed no marked phosphorylation (Figure 2).

We report here that BACE1+/− deletion is able to reduce cerebral Aβ42 and rescue deficits of 5XFAD mice in hippocampus-dependent spatial working memory in the spontaneous alternation Y-maze assay when tested at the relatively earlier stage (6 months of age), which develops moderate plaque pathology but shows no changes in BACE1 levels.

The classification/assessment of valvular function showed moderate-to-strong correlation and we found high specificity and high negative predictive values for detecting at least moderate valvular pathology.

However, Dmd mdx mice show a mild phenotype, with comparatively moderate muscle pathology, and muscle degeneration is followed by a large amount of regeneration (Dangain and Vrbova, 1984).