In our study LUS alone ruled in pneumonia with a good positive likelihood ratio and ruled out this condition with a moderate negative likelihood ratio.
3 A recent meta-analyses evaluating these two tests demonstrated, however, that they have only moderate negative likelihood ratios (stress echocardiography 0.23 and stress perfusion imaging 0.44), and that more than a third of the patients who suffered a major perioperative cardiovascular event had a negative preoperative test result.
Likelihood ratios were interpreted according to reported guidelines for interpreting changes in probability of disease status (positive likelihood ratio: small (2.0 to 5.0), moderate (5.0 to 10.0), large (>10); negative likelihood ratio: small (0.2 to 0.5), moderate (0.1 to 0.2), large (<0.1)) [ 37].
Cut-off values at the 50th centile had only a moderate sensitivity (0.84 (0.79 to 0.89)) and negative likelihood ratio (0.40 (0.29 to 0.56)), and could not rule out the presence of lower respiratory tract infections.
Cut-off values at the 50th centile had a moderate sensitivity of 0.84 (0.79 to 0.89) and negative likelihood ratio of 0.40 (0.29 to 0.56), and could not rule out presence of lower respiratory tract infections.
Three studies assessed the diagnostic accuracy of indirect radionuclide cystography[ 78, 84, 91]; positive likelihood ratios were moderate and ranged from 3.3 to 12.6, and negative likelihood ratios ranged from 0.15 to 0.63.
Another aspect of our study is that serum MDA levels could be used as a biomarker to predict the clinical outcome of septic patients according to the results of ROC curve analysis to predict 30-day mortality, although the test properties (sensitivity, specificity, positive and negative predicted values, and positive and negative likelihood ratios) for MDA to predict 30-day mortality are moderate.
The negative likelihood ratio (LR-) was very useful (<0.1) for bladder DIE and moderately useful (0.1-0.2 0.1-0.2arian endometriomas, moderate or severe ovarian adhesions, and pouch oforovarianadhendometriomas
The negative likelihood ratio (LR−) for BCG and LAM was similar and indicated moderate decrease in the likelihood of disease (0.1 0.2).
The sensitivity (0.56) and negative likelihood ratio (0.48) associated with this two-criteria rule were only moderate, indicating a relatively high potential for false negative results (i.e., subjects designated as likely non-responders who ultimately experienced success with manipulation).
The overall sensitivity, specificity, positive likelihood ratio, and negative likelihood ratio of the ultrasound for the detection of a moderate-severe fatty liver, as compared to histology, were sufficiently high compared with those of other imaging techniques (i.e., CT or MRI) [ 1].
